MRI Diffusion tensor imaging (DTI) diagnostic findings in schizophrenia
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Date
2022
Authors
Mariam Maen Omar
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Abstract
Schizophrenia is a wide spreading neurologic disease, that has been detected
increasingly in different countries around the world.
Verbal communication is known as the golden approach in psychology, it is used as the
main method for diagnosing psychiatric cases and even the follow up of the patient’s
improvement and rehabilitation.
This project, aims to highlight the importance of medical imaging techniques along the
therapeutic plan for the patient, The aim of the study to find if there’s a relationship between
schizophrenia and associated changes in the brain structure (arcuate fasciculus) which can use
later to find if these changes affect patient symptoms severity .and how it should be considered
as an effective guide for the improvement of the patient and how far does the treatment succeed.
This systemic review is about different studies that was done in order to declare the
differences of patients with unstable neurologic state ( schizophrenia in particular) and define the
changes that happens among the fiber tracts connectivity in the brain using a specific technique
especially for brain imaging which is Magnetic resonance imaging DTI (diffusion tensor
imaging), which is a special technique to evaluate fiber tracts of the brain and assess the fiber
connectivity and the neuron tracts (white matter).
The results that was concluded from different studies and reviews of the MRI
tractography technique showed a several neurological changes among the brain and its tracts, and
that schizophrenia can be assessed by the MRI DTI technique along its symptoms severity, and
these radiographic signs might include: The degenerating of the neuro-tracts can be more evident4
on the left lobe of the brain: including long segments of the arcuate fasciculus (AF) fiber bundle.
It also showed increased RD and Trace of the left external capsule, and decreased AD of the
right SLFd along with decreased volume of the left SLFd indicating impairment of white matter
integrity in these areas.
The results suggest that the hallucinating schizophrenic group has a noted increased
connectivity between the auditory areas in the temporal lobe and frontal and parietal areas
associated with language.