MRI Diffusion tensor imaging (DTI) diagnostic findings in schizophrenia

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Mariam Maen Omar
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Schizophrenia is a wide spreading neurologic disease, that has been detected increasingly in different countries around the world. Verbal communication is known as the golden approach in psychology, it is used as the main method for diagnosing psychiatric cases and even the follow up of the patient’s improvement and rehabilitation. This project, aims to highlight the importance of medical imaging techniques along the therapeutic plan for the patient, The aim of the study to find if there’s a relationship between schizophrenia and associated changes in the brain structure (arcuate fasciculus) which can use later to find if these changes affect patient symptoms severity .and how it should be considered as an effective guide for the improvement of the patient and how far does the treatment succeed. This systemic review is about different studies that was done in order to declare the differences of patients with unstable neurologic state ( schizophrenia in particular) and define the changes that happens among the fiber tracts connectivity in the brain using a specific technique especially for brain imaging which is Magnetic resonance imaging DTI (diffusion tensor imaging), which is a special technique to evaluate fiber tracts of the brain and assess the fiber connectivity and the neuron tracts (white matter). The results that was concluded from different studies and reviews of the MRI tractography technique showed a several neurological changes among the brain and its tracts, and that schizophrenia can be assessed by the MRI DTI technique along its symptoms severity, and these radiographic signs might include: The degenerating of the neuro-tracts can be more evident4 on the left lobe of the brain: including long segments of the arcuate fasciculus (AF) fiber bundle. It also showed increased RD and Trace of the left external capsule, and decreased AD of the right SLFd along with decreased volume of the left SLFd indicating impairment of white matter integrity in these areas. The results suggest that the hallucinating schizophrenic group has a noted increased connectivity between the auditory areas in the temporal lobe and frontal and parietal areas associated with language.