Pharmaceutical Sciences
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Dual functionalization of single-walled carbon nanotubes for targeted cancer therapy
(An-Najah National University, 2018-05-07)Chemotherapy is a mainstay strategy in the management of cancer. Regrettably, they suffer from serious side effects due to their effect on healthy cells besides cancerous cells. Therefore, many researchers are eager to ... -
Formulation and Stability Evaluation of Ciprofloxacin Topical Preparation
(An-Najah National University, 2018-08-16)With increment the number of infections resistance to antibiotics and life threatening causes many researchers work on developing alternative approaches and manufacturing new drug delivery systems to traverse the disadvantages ... -
Functionalization of graphene sheets for the development of gene delivery system
(An-Najah National University, 2018-08-16)Graphene is considered a class of two-dimensional sp2 carbon nanomaterials which has attracted tremendous attentions for medicinal fields in the past decade, like gene and drug delivery. The using of graphene as a non-viral ... -
Pharmaceutical Dosage Form Preparation of a Synthesized Celecoxib Salt and Development of a Validated Method for its Analysis
(An-Najah National University, 2018-08-16)Background: Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) and cyclooxygenase-2 (COX-2) inhibitor. It is used in the treatment of rheumatoid arthritis, osteoarthritis, juvenile arthritis, and acute pain. ... -
Extemporaneous Compounding and Physiological Modeling of Amlodipine/Valsartan Suspension
(An-Najah National University, 2018-05-13)Background: In case of absent liquid dosage form, crushing a tablet or dispersing a capsule would be the most convenient option for using these drugs in patients with dysphagia difficulties. However, no bioequivalence or ... -
Chemical composition and pharmacological screening of Micromeria fruticosa serpyllifolia volatile oils collected from West Bank-Palestine
(An-Najah National University, 2018-02-26)Background and Objectives Micromeria fruticosa subspecies serpyllifolia (M. Bieb.) is one of the Medicinal Aromatic Plants (MAP) which are dominated in the eastern Mediterranean regions including Palestine, has pleasant ... -
Bio-Functionalization of SWCNTs with Combretastatin A4 for Targeted Cancer Therapy
(An-Najah National University, 2017-05-25)Chemotherapy is a mainstay approach in the management of cancer. Unfortunately, it can affect not only the cancerous cells but also the healthy ones resulting in a number of severe side effects. Therefore, many researchers ... -
Synthesis, characterization & biological activity of Isopropyl Thiazole derivatives of the natural products Distamycin & Proximicin
(An-Najah National University, 2017-05-04)Minor groove binders (MGBs) are molecules which bind selectively to the minor groove of DNA. Distamycin and netropsin are naturally occurring MGBs, and are members of the polypyrrole class of compounds. They have potential ... -
Synthesis, Formulation and Analytical Method Validation of Rutin Prodrugs
(An-Najah National University, 2017-11-01)Background: Rutin is a plant extract that belongs to the flavonoid group of compounds. Many studies showed that Rutin has a potential pharmacological uses such as antioxidant, anti-inflammatory and antihypertensive activities. ... -
Evaluation of Food Effect on the Absorption of Clarithromycin using Physiological Modeling
(جامعة النجاح الوطنية, 2017-08-08)Background: Food may affect the oral absorption of drugs by inducing physiological changes in the gastrointestinal physiology, such as: gastrointestinal pH, gastric residence time, bile salt secretion and drug metabolism. ... -
Functionalization of graphene sheets and their antibacterial activity
(An-Najah National University, 2017-08-08)Graphene is a thin flat monolayer of carbon atoms tightly packed into a two-dimensional (2D) honeycomb lattice. It is one of the most studied materials nowadays because it has a high surface area and unique properties. ... -
Biological and phytochemical screening of Erodium laciniatum and Lactuca orientalis
(An-Najah National University, 2017-01-12)From ancient times, various herbal remedies and various medical agents containing flavonoids, tannins and phenols have been utilized for prevention and treatment of different diseases and disorders. Currently, such groups ... -
Preparation and Characterization of Carvedilol-Loaded Poly (D, L) Lactide Nanoparticles/Microparticles as a Sustained Release System
(2015)Background: Polymeric nano and micro particles are promising delivery systems for the enhancement of the bioavailability of highly lipophilic drugs prone to first pass metabolism. Purpose: This study aims at preparing ... -
Analytical and Dissolution Method Development and Validation for a Home Formulated Rutin Tablet
(2015)Rutin can be classified as flavone, colorant and vitamin. It is highly available in some foods, fruits, vegetables and plant-based beverages. Rutin is highly attracted to the researchers due to its variant beneficial medical ...
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