THE EFFECTS OF USING AUTOLOGOUS PLATELET-RICH PLASMA VERSUS TRADITIONAL MEDICAL MANAGEMENT TO IMPROVE WOUND HEALING PROCESS IN CRITICAL ILL PATIENT: A COMPARISON STUDY FROM PALESTINE

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dc.contributor.authorHalaika, Rami
dc.date.accessioned2025-01-09T13:23:44Z
dc.date.available2025-01-09T13:23:44Z
dc.date.issued2024-10-14
dc.description.abstractBackground: Chronic and poorly healed wounds represent a failure in achieving complete re-epithelialization in the appropriate sequence of tissue repair. Impaired healing process has been related to numerous inherent causes, such as neuropathy, vascular problems in addition to extrinsic factors such as wound infection and trauma. There are many methods can be used for chronic wound management. One of these techniques is autologous platelet-rich plasma (PRP), It has the potential to enhance chronic wound healing and contains fibrin along with high concentrations of platelets and growth factors. Objective: to assess the effects of using Autologous Platelet-Rich Plasma in improving wound healing in chronic wounds in comparing to the traditional medical management used in critical ill patient in Palestine. Methods: retrospective, comparison study between 20 critical ill patients with chronic poorly healing ulcers divided in two equal groups. One group was received Autologous Platelet-Rich Plasma at critical care unit, while the other group treated by daily dressing. Both groups was followed over period of time (2years) 2020-2022 to assess the difference in healing presses between them. The results showed that the diabetes was the most common medical history illness among ICU patients with chronic wounds (50%), followed by IHD (45%) and hypertension (40%). While ESRD occurred at a 10% prevalence, 35% of those affected had additional chronic conditions. 75% of the ICU patients with chronic wounds had a positive surgical history. Finally, 70% of ICU patients with chronic wounds had a positive family history. Although the percentage of individuals with a history of hypertension and IHD were greater among the ICU patients with chronic wound participants in the PRP group than in the ICU patients with chronic wound in the conventional group (62.5% & 66.7% vs. 37.5% & 33.3%), no group nor demographic characteristic could predict the development of chronic wounds and poor wound healing in Palestine among ICU patients, as the p values for all factors were more than 0.05. The model was not statistically significant (F=.809, p=.597) but could predict roughly 32% of the variance. Conclusions: among ICU patients in Palestine , PRP is beneficial and effective in improvement the healing process in chronic wounds, but to a less than treatment with traditional methods, as the complete healing rate in the group in which traditional treatment was used was 63.5%, while the other group was 36.5%, and this is consistent with some studies that were used. The same tool that’s used in my study.
dc.identifier.urihttps://hdl.handle.net/20.500.11888/19794
dc.language.isoen
dc.publisherAn-Najah National University
dc.supervisorQaddumi, Jamal
dc.titleTHE EFFECTS OF USING AUTOLOGOUS PLATELET-RICH PLASMA VERSUS TRADITIONAL MEDICAL MANAGEMENT TO IMPROVE WOUND HEALING PROCESS IN CRITICAL ILL PATIENT: A COMPARISON STUDY FROM PALESTINE
dc.title.alternativeتأثير استخدام البلازما الذاتية الغنية بالصفائح الدموية مقارنة بطرق الرعاية التقليدية المتبعة لتحسين عملية التئام الجروح: دراسة مقارنة من فلسطين
dc.typeThesis
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