DEXMEDETOMIDINE AS A BLOCKING AGENT FOR INTERCOSTAL BLOCKS IN PATIENTS WHO UNDERGO VIDEO -ASSISTED THORACOSCOPIC SURGERY
dc.contributor.author | Mousa Mohammed Mousa Ma’rouf | |
dc.date.accessioned | 2024-06-09T19:51:43Z | |
dc.date.available | 2024-06-09T19:51:43Z | |
dc.date.issued | 2022-06-29 | |
dc.description.abstract | Background: Local or regional anesthesia is one major fields in anesthesia. One technique to apply regional anesthesia is intercostal block, a type of regional anesthesia used in thoracic and upper abdominal surgeries to provide analgesia and to relieve pain due to rib-fracture, cancer, thoracic procedures and lung surgeries. Video -assisted Thoracoscopic Surgeries (VATS) has been began the late 20th century. They have now become one of the most common preferred procedures for lung surgeries. Applying intercostal blocks in these surgeries yield good outcome on pain level post operatively. Many anesthetic blocking agents are used in regional anesthesia such as lidocaine and Marcaine. Dexmedetomidine is an alpha-2 adrenergic antagonist that works on the smooth muscles of viscera and has unique effect on pain control and sedation. Adding 1 microgram per kilogram of Dexmedetomidine for the formula has a strong effect on controlling level of pain. Objectives: This study has assessed the effect of Dexmedetomidine as intercostal block agent on the level of pain, analgesia requirements, stability of hemodynamics and nausea and vomiting. Methodology: randomized control clinical trial double-blinded design was used to assess 30 patients with a category of anesthesia (ASA 1, ASA 2 and ASA 3) who underwent VATS in referral center in Palestine. These patients were divided into two groups: intervention (experimental) and control. The control group (15 patients) was given Marcaine 1 mg/kg while, the intervention group was given 1 microgram/kg Dexmedetomidine with 1 mg/kg Marcaine on intercostal space. Results: According to the results, there was an effect on the level of pain in the 3rd (p-value=0.04) 5th (p-value=0.01) 15th (p-value=0.1) minute post operation and after 24 hours of the procedure (p-value=0.01). Conclusion: Using Dexmedetomidine as adjunct in intercostal block deceased the intensity of pain, conserved the vital signs (hemodynamics) on the normal lower limits for patient, and needed less analgesic requirement post-operatively. There was also no incidence of nausea and vomiting for patients who were administered Dexmedetomidine with Marcaine. Keywords: Dexmedetomidine, intercostal block, regional anesthesia, pain, analgesia, hemodynamics. | |
dc.identifier.uri | https://hdl.handle.net/20.500.11888/19043 | |
dc.language.iso | en | |
dc.supervisor | Dr. Jamal Qaddumi | |
dc.title | DEXMEDETOMIDINE AS A BLOCKING AGENT FOR INTERCOSTAL BLOCKS IN PATIENTS WHO UNDERGO VIDEO -ASSISTED THORACOSCOPIC SURGERY | |
dc.type | Thesis |