PREDICTORS OF ADMISSION, OUTCOMES, SURVIVAL, AND MORTALITY RATES IN MEDICAL ICU ADULT SEPSIS PATIENTS IN A TERTIARY CARE HOSPITAL: A RETROSPECTIVE STUDY
No Thumbnail Available
Date
2024-08-04
Authors
Ashqar, Elias
Journal Title
Journal ISSN
Volume Title
Publisher
An-Najah National University
Abstract
Background: Sepsis is a serious illness that results from the body's overreaction to an infection. Because of its high mortality rate, high treatment costs, and long-lasting effects on survivors, Unanimous treatment techniques, early detection, and awareness are critical due to diagnosing challenges and the need for timely treatment.
Aim: to evaluate the predictability of admission, outcomes, survival, and mortality in ICU Adult Patients admitted to medical ICU who developed sepsis in a tertiary care hospital.
Method: A retrospective study design from 2018 to 2023 was carried out the sample size consisted of 326 patients. The focus of this study was on patients who had been identified as having sepsis attending An-Najah National University Hospital (NNUH). The instrument for collecting data used in the present study was demographic, clinical, laboratory data, and predictive tools enrollment from the electronic health record system and patient survival.
Results: The results showed that 135 patients (41.41%) did not survive, whereas 191 patients (58.59%) did. It was discovered that these patients' mortality was not significantly influenced by their demographics. Many clinical variables, however, were significantly associated with death, indicating their potential as predictors of sepsis outcomes. These variables included systolic blood pressure, heart rate, Glasgow Coma Scale, HCO3, PH, total serum bilirubin, serum sodium, albumin, serum lactate, and systemic inflammatory response syndrome. Furthermore, there was a strong correlation between death and the presence of cancer in sepsis patients. Predictive measures such as APACHE II, SOFA, and SAPS II were found to be highly effective in predicting death in patients with sepsis.
Conclusion: Among sepsis patients, age and gender were not significant predictors of admission to the medical ICU. Yet, several parameters showed promise as predictors of ICU admission in sepsis cases, including systolic blood pressure, heart rate, Glasgow Coma Scale, HCO3, pH, total serum bilirubin, serum sodium, albumin, serum lactate, and systemic inflammatory response syndrome. Furthermore, there was a correlation between having cancer and a higher risk of sepsis.
Keywords: sepsis, medical intensive care unit, modified early warning signs, APACHE II, SOFA, SAPS II, predicting in-hospital, An-Najah National University Hospital.