THE EFFECTIVENESS OF LORAZEPAM IN PREVENTING RADIAL ARTERY SPASM IN PATIENTS HAVING RADIAL APPROACH CARDIAC CATHETERIZATION A DESCRIPTIVE STUDY

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dc.contributor.authorkittaneh, Qadri
dc.date.accessioned2026-02-26T09:52:34Z
dc.date.available2026-02-26T09:52:34Z
dc.date.issued2026-02-17
dc.description.abstractBackground: One of the frequent complications in transradial cardiac catheterization is the spasm of the radial artery (RAS). This problem sometimes results in pain for the patient and makes the medical procedure difficult. Certain psychological factors, such as anxiety and pain, lead to activation of the sympathetic vascular responses, thereby raising the chance of RAS. Aim: This study intends to investigate the link between administration of lorazepam and the incidence of radial artery spasm in patients who undergo transradial cardiac catheterization, while considering the levels of anxiety and pain as one of the factors. Methodology: A descriptive observational study with a sample of 189 patients having tranradial cardiac catheterization was done in Nablus Specialty Hospital from February to August 2025. Depending on the standard clinical practice and the doctor's judgement, the participants were divided into two groups: the first group (n = 61) consisted of those who received oral lorazepam, and the second group (n = 128) of those who did not receive lorazepam. The level of anxiety was determined by the Hospital Anxiety and Depression Scale Anxiety subscale (HADS, A), and the pain intensity during the procedure was evaluated using the Visual Analog Scale (VAS). Samples associations have been tested by chi, square and the criterion for statistical significance was that p < 0.05. Results: In the lorazepam group, 34.3% of the patients had RAS compared to 42.2% in the non, lorazepam group. In the group that did not have lorazepam, it was found that high levels of anxiety and pain were significantly (p < 0.05) associated with the occurrence of RAS while there is no such significance as observed from lorazepam group. Female gender and lower education level were found to have a significant effect on the higher incidence of RAS (p < 0.05) whereas age, body mass index, smoking status, and comorbidities did not show such an effect. Anxiety levels after the procedure went down in both groups and more patients achieved normal anxiety scores. Also, pain intensity during the procedure was lower among the patients who took lorazepam. Conclusion: Taking lorazepam brought about lowered anxiety and pain levels, along with the reduced occurrence of radial artery spasm in the transradial catheterization. Causality cannot be determined owing to the design of the observational study. Recommendations: To confirm the role of lorazepam in the prevention of RAS, future researchers should use randomized controlled trials. Besides, more studies should be done to investigate long, term vascular outcomes and to compare lorazepam with other anxiolytic agents.
dc.identifier.urihttps://hdl.handle.net/20.500.11888/20888
dc.language.isoen
dc.publisherAn-Najah National University
dc.supervisorAlkaissi, Aidah
dc.supervisorAlmasri, Nouraldin
dc.titleTHE EFFECTIVENESS OF LORAZEPAM IN PREVENTING RADIAL ARTERY SPASM IN PATIENTS HAVING RADIAL APPROACH CARDIAC CATHETERIZATION A DESCRIPTIVE STUDY
dc.title.alternativeفعاليه لورازيبام في الوقايه من تشنج الشريان الكعبري لدى المرضى الذين يخضعون لقسطره القلب الشعاعيه ز دراسه
dc.typeThesis
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