Thirty-Days of Survival, Patients Undergoing Intermittent Hemodialysis Versus Sustained Low Efficacy Dialysis for Acute Kidney Injury: A Retrospective Study

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ابو طير, هويدا عيسى داوود
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An-Najah National University
Background: Acute kidney injury (AKI) is progressively common and is brought into relation with high costs and un preferably clinical outcomes like complications of RRT which the most common is hypotension that reaches to 30-70%, long length of stay, high mortality rates up to 50-70%, however if the intervention to start renal replacement therapy was made early, it will enhance the outcome and mortality rate. The aim of this study is to determine the mortality rate, clinical characteristics & outcomes of intermittent hemodialysis (IHD) versus sustained low efficiency dialysis (SLED) among critically ill patients with AKI. Methods: This study was a retrospective cohort design performed at a An-Najah National University Hospital in the west bank which is recruiting 50 patients treated with either IHD or SLED in the intensive care unit (ICU). It included the patient’s demographic data, past history, indications for dialysis modalities, hemodynamic parameters and lab test parameters which were tested pre- and post-dialysis for three sessions, complications of dialysis and finally renal outcome which were viewed and analyzed. Results: Median age was 57.2 years with interquartile range of 8.8 years, 80% of them were 50 years, 68% were male in gender, 66% were on mechanical ventilation and 40% were on vasoactive drugs, acute physiology, assessment, chronic health evaluation (APACHE) score p value <0.038, median sequential organ failure assessment score (SOFA) score was 0.45 with interquartile range of 0.28. The major complication was hypotension 56%, and 46% of patients were not recovered (died or end stage renal failure). Conclusion: Our study showed that the recovery of AKI was associated with younger and educated patients while the non-recovery was associated with older patients whom suffering from medical history regarding to the modality was used in the treatment. Keywords: Acute kidney injury, Intermittent hemodialysis, Sustained low efficiency dialysis, Mortality rate, Clinical characteristics, Outcomes.