Effects of Daily Supplementation with High Dose Ascorbic Acid on Blood Lead Levels in Broiler Chicken after Intentional Exposure to a Concentrated Source of Lead

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dc.contributor.authorAhed Zyoud
dc.contributor.authorHikmat S. Hilal
dc.contributor.authorMohammad Abd-Aldaym
dc.contributor.authorOmar Abubaker
dc.contributor.authorRamzi Shawahna
dc.contributor.authorSawsan Abu-Rwess
dc.contributor.authorSuheir Shehadeh
dc.contributor.authorTamara Idkeidek
dc.date.accessioned2017-04-20T07:22:05Z
dc.date.available2017-04-20T07:22:05Z
dc.date.issued2016
dc.description.abstractLead toxicity is an important global public health issue. The present study was conducted to determine the amount of lead deposited in chicken blood after intentional exposure to a concentrated source of lead for 1 week and to determine the effect of 4 week daily supplementation with high dose ascorbic acid (AA) on the blood lead levels in broiler chicken. Clinically normal mixed-breed adult laying chickens were used in this study. Chickens received lead acetate (200 mg/kg/day) for 1 week. A group of chicken received AA (500 mg/kg/day) for 4 weeks. Another group did not receive any treatment for another 4 weeks. Blood samples were collected and analyzed for blood lead levels using a graphite furnace atomic absorption spectrophotometer. The baseline blood lead level was 47.5 ± 38.0 µg/L and increased significantly to 2755 ± 576 µg/L after 1 week of lead acetate treatment (P < 0.001). AA treatment reduced blood lead levels significantly (P < 0.05). Supplementing lead-contaminated feed with daily high doses of AA might protect from lead exposure when chickens are exposed to environmental pollution.en
dc.identifier2413-8568
dc.identifier.urihttps://hdl.handle.net/20.500.11888/3152
dc.titleEffects of Daily Supplementation with High Dose Ascorbic Acid on Blood Lead Levels in Broiler Chicken after Intentional Exposure to a Concentrated Source of Leaden
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Palestinian Medical and Pharmaceutical Journal (PMPJ)