THE EFFECT OF CO2 INSUFFLATION ON ARTERIAL BLOOD GASES AND END TIDAL CO2 DURING LAPAROSCOPIC SURGERIES IN ADULTS

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Date
2024-10-14
Authors
Souqi, Mohammad
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An-Najah National University
Abstract
Theoretical background: During laparoscopic surgeries, surgeons prefer to inflate the abdomen using CO2 gas to make a space between abdominal layers and organs and the " pneumoperitoneum " procedure. Clinical significance was found, and the effect of CO2 insufflation on end-tidal CO2 levels and arterial blood gases was clarified during these procedures, especially in terms of patient ventilation and respiratory function. Aims: The purpose of the study was to discover the effect of co2 inflation during laparoscopic operations on the end-tidal co2 levels and arterial blood gases for adults patients. The main goal was to evaluate the physiological effects of CO2 insufflation and its connection with respiratory parameters. Methodology: 60 adult patients who underwent laparoscopic surgery were selected and divided into two groups with 30 participants in each group based on respiratory rate used and the study design was a prospective single-blind quasi-experimental design. Patients were monitored for ABG, vital signs and ETCO2 levels. Subgroup and sensitivity analysis were applied to assess the effect of CO2 insufflation on vital signs and respiratory system functions. Main results: The results showed significant differences in ABG and ETCO2 levels among the two groups, especially in respiratory rate, duration of CO2 insufflation and venting of CO2. Subgroup analysis showed changes in ABG based on the duration of CO2 insufflation, and sensitivity analysis indicated the possible effect of confounding variables on the study outcomes. Conclusions: The findings assure on the importance of carefully monitoring and managing CO2 levels during laparoscopic surgeries to provide optimal patient outcomes and gives important information about the physiological implications of CO2 insufflation, and emphasizes the need of standardized protocols and continuous monitoring during these surgical procedures. Keywords: Arterial Blood Gases (ABG), CO2-Insufflation, End-Tidal CO2 (ETCO2), Laparoscopic Surgeries and Respiratory Rate (RR).
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