Size Selective Synthesis of Sulfur Nanoparticles and their Anti Cancer Activity
Date
2015-04-21
Authors
Al-Ali, Anas
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Journal ISSN
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Abstract
Sulfur is an important element with many practical applications when
present as nanoparticles. Nanosize sulfur particles also have many important
applications like in pharmaceuticals, medicine, synthesis of nano-composites for
lithium batteries, modification of carbon nano tubes [1]. Different methods were
used for nano-sized particle synthesis; among those, chemical precipitation,
electrochemical method, micro emulsion technique, composing of oil, surfactant,
co-surfactant, aqueous phases with the specific compositions and ultrasonic
treatment of sulfur-cystine solution [2]. In this work sulfur nanoparticles (S NPs)
were prepared by a quick precipitation method with and without using a
surfactant to stabilize the formed S NPs.
The synthesized S NPs were characterized by XRD, SEM and TEM in order to
confirm their sizes and structures.
Application of nanotechnology is suggested for diagnosis and treatment of cancer
[3]. The anticancer activity of the prepared S NPs has been tested on various types
of cancer cell clones including leukemia, kidney and colon cancers.
The desired S NPs revealed a high
promising activity and selectivity
toward killing kidney cancer .
References:
[1] P. Santiago, E. Carvajal, D.M Mendoza, L. Rendon. (2006) Synthesis and Structural
Characterization of Sulfur Nanowires. Microsc. Microanal., 12,690.
[2] M. Suleiman, A. Al Ali, A. Hussein, B. Hammouti, T.Hadda, I.Warad. (2013) Sulfur
Nanoparticles: Synthesis, Characterizations and their Applications. J. Mater. Environ. Sci.,
4, 1029-1033.
[3] F.Alexis, E.Pridgen, L.Molnar, O.Farokhzad. (2008) Factors affecting the clearance and
biodistribution of polymeric nanoparticles. Mol. Pharmacol, 5, 05–15.
Description
Keywords
Sulfur Nanoparticles (SNPs)