The Fifth Palestinian International Chemistry Conference

Recently, nanoparticles biological and medical applications is gaining a great interest becauseof their great positive influence in finding novel innovations and solving escalating medicalproblems like the multi drug resistance in infectious microorganisms that threaten the worldof not finding a curing drug. Nanoparticles of different physical and chemical properties are ofprimary concern to find a compound with antibacterial activity. Moreover, the ability tosynthesis nanoparticles in different shells; ranging from pure chemical to natural materialsopen new era of investigating the antipacterial activity and finding the magical antibacterialdrug. In this study, different forms of metallic nanoparticles synthesized in different shellswill be investigated for their antibacterial activities.Size selective synthesis of ZnO nanoparticles is being prepared by electrochemical and/orreduction methods. Two forms of stabilization; with alkyl quaternary ammonium compoundssurfactants and with quaternary surfactant in combination with antibiotics are in progress toinvestigate their antibacterial activity. Primarily, antibacterial activity presented by theminimum inhibitory concentration of the different forms of the prepared nanoparticles isbeing evaluated spectrophotometrically or visually. The reference materials and theindividual nanoparticles possess a relative antibacterial activity. A more detailed analysis ofthe nanoparticles prepared with tetra-alkyl ammonium salt as stabilizing matrix and tetraalkylammonium salt with amoxicillin is now in progress.