Water Soluble Novel Dicationic [Cu(phen)(N3)]Br2 Complexes: DNA-binding and Bio-logical Activities
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Novel water soluble dicationic copper(II) complexes, of general formula [Cu(phen)(NNN)]Br2 [phen = 1,10-phenanthroline , NNN= diethelenetriamine (dien) and dipropylenetriamine (dipn)], have been prepared. The structures of the desired complexes were characterized by spectroscopic, element analysis, Uvvisible, IR, thermal and X-ray crystallographic techniques. These complexes exhibit a promising antimicrobial effect against an array of microbes at 200 µg/ml concentration. The absorption spectra of such complexes were modeled by timedependent density functional theory (TD-DFT) and the absorption maxima around 620 nm and 280 nm are assigned to the d–d and Phen(π) →Phen(π٭) transitions, respectively. Absorption spectral studies revealed that such complexes exhibit strong CT-DNA binding.